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Provedor de dados:  BABT
País:  Brazil
Título:  The effects of low level laser therapy on injured skeletal muscle
Autores:  Renno,Ana Claudia Muniz
Assis,Lívia
Peres,Beatriz
Rodrigues,Natalia Camargo
Brunelli,Roberta de Matos
Toma,Renata Luri
Medalha,Carla Christina
Ribeiro,Daniel Araki
Data:  2014-02-01
Ano:  2014
Palavras-chave:  Low level laser therapy
Rat
Muscle repair
COX-2
Resumo:  The main purpose of the present study was to investigate the effects of low-level laser therapy (LLLT) used in two different fluencies on injured skeletal muscle after cryolesion by means of histopathological analysis and immunohistochemistry for COX-2. A total of sixty male Wistar rats were randomly distributed into three groups: injured animals without any treatment; 808 nm laser treated group, at 10 J/cm² and 808 nm laser treated group, at 50 J/cm². Each group was divided into two different subgroups (n=10) on days 6 and 13 post-injury. The results showed that the animals irradiated with laser at 10 J/cm² or 50 J/cm² presented the areas with cell infiltrate and pointed out to minor and mild areas with destroyed zones compared with the control group. Also, a COX-2 downregulation was noticed in the groups exposed to laser at two fluences evaluated in this study. Significant statistically differences (p<0.05) were noticed to collagen deposition in the laser treated animals, with the fluence of 50 J/cm² when compared to the other groups on day 13 post-surgery. Taken together, these results suggested that laser therapy could have positive effects on muscle repair in the rats after cryolesion.
Tipo:  Info:eu-repo/semantics/article
Idioma:  Inglês
Identificador:  http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132014000100008
Editor:  Instituto de Tecnologia do Paraná - Tecpar
Relação:  10.1590/S1516-89132014000100008
Formato:  text/html
Fonte:  Brazilian Archives of Biology and Technology v.57 n.1 2014
Direitos:  info:eu-repo/semantics/openAccess
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